Regenerative Medicine Atlanta

PRP Injections in Atlanta.

Call (404) 772-8355

Soccer athlete, orthobiologics in focus
Regenerative Medicine PRP Injections Common in soccer, running, and tennis
Quick answer

Recovery after a PRP injection

PRP is short for platelet-rich plasma, and recovery depends on what was actually done. A joint injection and a tendon procedure carry completely different protocols and precautions, even though both get called PRP.

After a joint injection, many people simply walk out and carry on with their day. After a tendon procedure, you may need a brace, crutches, or a cane. The difference is not caution for its own sake: a joint injection touches nothing but skin on the way in, while a tendon procedure passes the needle through the damaged tissue itself.

The rule after a tendon procedure is protect, then mobilize, then strengthen, and return to sport only after all three. Each phase depends on the one before it, not on how many days have passed since the shot. That is why your written protocol beats anything you find online.

Some soreness afterward is normal, particularly after soft tissue work. This is not the same as symptoms that should prompt a phone call. Call the provider if you have a fever, a rash, or drainage from the site. The same goes for new numbness or weakness in the injected limb, or pain that keeps climbing instead of easing.

Improvement is not something you notice on the drive home. It is judged at a follow-up visit, sometimes several, against the goals set beforehand. That goals-first frame is the heart of regenerative medicine as this practice approaches it, and it is set before any needle comes out.

Why PRP rather than a gel injection

Both a gel injection and a PRP injection are injected via a needle into an injured joint, and that is where the similarities end.

Neither injection regenerates lost cartilage, and how long relief lasts differs between patients. A success rate quoted without naming the joint, the severity, and the patient is a statistic with the questions removed. The argument for a platelet product is not that it beats the gel; it is that it aims at a different target.

  • What is in the syringe.

    Viscosupplementation is the medical term for a gel injection, where the gel itself is made up of hyaluronic acid, and it's put in the joint to lubricate it.

    PRP begins as a sample of your own blood. A centrifuge spins it to gather the platelets into a smaller volume of liquid, and that concentrate goes back into you.

  • What each one is trying to change.

    A gel injection targets lubrication and the pain that follows its loss. Platelet-rich plasma targets the biological signals around the damaged tissue, since platelets secrete proteins involved in repair.

    Two different targets, and the difference is the whole point.

  • Where each one can be used.

    A gel injection is a joint treatment. Platelet-rich plasma is also used around tendons and ligaments, a separate setting with its own evidence. A complete tear falls outside both: an Achilles tendon rupture is a mechanical problem, and no injection reattaches a tendon that has pulled apart.

  • What the risk conversation covers.

    The risks for any injection into a joint are roughly the same, including bleeding, infection, damage to surrounding tissue, a post-injection pain flare, or lack of improvement.

    The one real difference: a gel is a manufactured substance, so an allergic reaction is possible, a risk your own blood essentially does not carry.

Does PRP hurt?

★★★★★
My mom took me to see Dr. Langer. We are from Amelia Island. My local doctor highly recommended him. Wow. He was right.
Patient, Fernandina Beach, FL RateMDs review

There will be some pain, and how much depends on where the needle goes. A shot into a joint space feels much like other joint injections. One at a tendon involves passing the needle through the actual affected area, and the next few minutes are more uncomfortable. Whether or not you get anesthetized, and how, should all be discussed ahead of time.

The second question matters more, and it tends to arrive a day or two later, usually with alarm. Inflammation can actually increase after a PRP injection, especially if soft tissue is the area being treated. It's a pain flare-up, and it may be a normal side effect, not a sign that something went wrong. (It is also not a sign that things are working, which is the other common misreading.) Knowing a flare-up is coming makes it much easier to endure. Find out what the typical level of soreness is for the specific injection you're getting, and what is acceptable to take for the pain. You want to know these answers before you walk into the doctor's office, not after you walk out of it. A doctor who cannot describe the expected range of soreness for their own procedure has already told you something important.

But there are certain symptoms that do fall outside of the expected range. Any fever, spreading redness, drainage from the injection site, new numbness or weakness, or continued worsening of pain should be reported immediately to the doctor who administered the injection. That is not the moment to tough it out.

PRP compared with BMAC, A2M, and adipose options

If you read anything about platelet-rich plasma, you'll soon encounter three more acronyms. Usually they're thrown around without any explanation. They vary in terms of what is being collected, how it's prepared, and the amount of human research that supports the treatment you're seeking. The first two are what stem cell therapy refers to here.

One rule covers all three: what matters is not the product but how much human data exists for it in your own diagnosis, and the knee's answer is not the shoulder's. None of the usual reassurances amounts to permission, either; registered somewhere, listed in a trial, and made from your own body are three different things.

  • Bone marrow concentrate, drawn from the pelvis.

    BMAC starts with marrow that's withdrawn via a needle, then processed to concentrate platelets, signaling proteins and a mix of cells, of which stem cells represent a tiny portion.

    Compared with a platelet preparation, the draw comes from a different place and carries a different mix.

    A systematic review of the randomized trials has found no evidence of superiority over the treatments it was pitted against.

  • Fat-derived preparations, taken from a small fat sample.

    MFAT, short for microfragmented adipose tissue, starts from a small sample of your own fat, processed mechanically into fragments that keep their native structure. Lipogems is the device name you will see attached to it.

    It is not a blanket term for every fat-based therapy, and it is not the enzyme-digested or lab-grown products some clinics offer.

    A trial in knee arthritis compared the fat preparation against platelet-rich plasma and found improvement in both groups, with no clear winner.

  • Alpha-2-macroglobulin, a protein already in plasma.

    Alpha-2-macroglobulin (A2M for short) is a protein that circulates in blood plasma and is touted as an anti-inflammatory treatment. To compare it responsibly with any PRP preparation, you would need to know which PRP product, its legal status, and the trials using it for the diagnosis at hand. Anything less is comparing acronyms.

How Atlanta Sports Medicine Institute uses PRP

PRP can be an option here; it is not an answer for every painful joint. Candidacy depends on the condition, its location, your goals, and what the data supports, and three of those four cannot be read off a search page.

The process remains the same. First, we make a diagnosis based on your symptoms, physical exam and any imaging that might change our treatment approach. We then consider all standard treatments including exercise, changes in activity levels, bracing and surgical procedures if there is damage that needs fixing. When a biologic makes the cut, it sits inside a treatment plan that names the goal and sets a date to judge whether it worked. If a steroid shot is on the table instead, the alternatives to cortisone injections are worth reading first.

The strongest research on platelet preparations sits in the knee, which is why knee pain is the most frequent way this conversation opens, though not the only one. The other research focus is chronic tendon trouble, and neither body of evidence settles every joint.

That judgment comes from reading the evidence, and from staying inside the professional debate while it remains unsettled. Two entries from the surgeon's record show where that reading comes from: Delivered more than 25 national and international presentations, and Member of the International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS).

Atlanta patients often arrive set on an injection, having read plenty about the products and little about which one fits their diagnosis. The first appointment usually goes to exactly that question. Request an appointment and begin with the examination.

Weightlifter standing at lockout with a barbell held overhead, shoulders, elbows, wrists, hips, knees and ankles glowing blue against a dark studio background
Your appointment

Start with clarity about your joint.

If pain is limiting the way you train, work, sleep, or move, an evaluation can turn uncertainty into a practical next-step plan.

Book an appointment →
  • A focused conversation

    Explain what you want to return to, not only what hurts.

  • A whole-joint assessment

    Look for the combination of findings that best explains the symptoms.

  • A clear next-step plan

    Understand the likely cause, whether imaging helps, and what comes next.

Atlanta Sports Medicine Institute

Care built around diagnosis, clarity, and durable function.

Atlanta Sports Medicine Institute helps active patients understand what may be driving their symptoms and compare appropriate treatment paths. The experience should be precise, understandable, and tied to the activities each patient wants to return to.

Diagnosis before treatment assumptions Nonsurgical and surgical options discussed in context Clear expectations without guaranteed outcomes A plan shaped by function, goals, and the structures involved
FAQ

Common questions.

Book an appointment →
What should I expect after a PRP injection?

Some soreness at first, written instructions suited to the area injected, and a follow-up visit to judge whether it helped. The written advice will be more specific for each structure injected, so don't rely on these general notes for post-injection activity. Joint injections have different restrictions than injections to tendons. Do not expect a verdict on the drive home. Any improvement will be gradual and should be compared with what was hoped for before you were injected. Soreness afterward is expected and should not be seen as an indication that something has gone wrong.

How long after PRP can I get a cortisone injection?

No published interval fits every patient. The answer lives with the doctor who knows what was injected, where, and why. Determining how long to wait between injections into the same site is a judgment call. It is also worth asking whether another steroid shot is the right move at all. Cortisone quiets inflammation but does not heal the underlying problem, and the alternatives to cortisone injections are a question in their own right. The sequencing follows the exam, not the calendar.

How long do PRP results last?

No one number applies to everyone. How long relief lasts differs between patients and depends on the diagnosis and the degree of structural damage. A study reports an average for a group at one follow-up, not a promise to anyone in it. The more important questions are what would be a response to treatment for you, when is it going to be re-evaluated, and what happens if there isn't a response. Improvement of symptoms is not the same as improvement of joint structure and these two things are lumped together more often than they should be.

Ready to be seen? Book an appointment.

Tell us what is bothering you and we will get you in front of the right person.